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Protein Misfolding

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There has been a lot of recent research on protein misfolding in preeclampsia [1], including a new Congo Red Dot test [2] for preeclampsia. I added some info to the article. — Preceding unsigned comment added by 24.205.82.168 (talkcontribs)

References

  1. ^ "Preeclampsia may share cause with disorders such as Alzheimer's", Science Daily, 2014-07-16, retrieved 2019-03-11
  2. ^ Rood, Kara; Buhimschi, Catalin; et al. (2019), "Congo Red Dot Paper Test for Antenatal Triage and Rapid Identification of Preeclampsia", EClinicalMedicine, doi:10.1016/j.eclinm.2019.02.004

PET as abbreviation

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Pre-eclampsia is in some books (including the Oxford Handbook of Clinical Specialties, 8th edition) is abbbreviated as PET, pre-eclamptic toxaemia. I personally don't like the word toxemia and also in medicine PET it is most known as an abbreviation for an imaging test of nuclear medicine, and although the abbreviation PET for pre-eclampsia is not widespread, I think it should be referred to the definition in this article 84.205.241.2 (talk) 18:59, 9 September 2016 (UTC)[reply]

Done Doc James (talk · contribs · email) 01:10, 10 September 2016 (UTC)[reply]

Timing: Three month disparity requires clarification

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The first paragraph speaks of onset after 20 weeks. The fourth paragraph says that onset is usually at 32 weeks. This is a difference of three months. These figures should be brought together and the apparent conflict explained by an authoritative source. Logic suggests at least four possible explanations, but speculation is pointless and potentially harmful. A professional should clarify this.Merry medievalist (talk) 12:16, 30 April 2020 (UTC)[reply]

Definition of pre-eclampsia

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I don't see a clear definition. The intro says "Pre-eclampsia is a disorder of pregnancy characterized by the onset of high blood pressure and often a significant amount of protein in the urine." Does this mean high blood pressure is always pre-eclampsia? If so, then pre-eclampsia is simply high blood pressure after the 20th week of pregnancy. However, I don't think that is what is meant, for two reasons.

  • The Cleveland Clinic says "Preeclampsia is a serious blood pressure condition that develops during pregnancy. People with preeclampsia often have high blood pressure (hypertension) and high levels of protein in their urine (proteinuria)."[1] The word "often" tells me this is not the definition of pre-eclampsia.
  • The WP article says "In general, none of the signs of pre-eclampsia are specific", which means I can't tell from symptoms whether pre-eclampsia is occurring. How does a doctor know?

I would like to see a definition. For instance, we know what we mean by pneumonia: "Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli." That isn't absolutely precise, which is okay, but I'm not convinced that high blood pressure is what we mean by pre-eclampsia, or it would be called "high blood pressure". Maybe I'm wrong, but I would like to see more clarity in the article (and at the Cleveland Clinic). Zaslav (talk) 01:56, 3 August 2022 (UTC) Zaslav (talk) 01:56, 3 August 2022 (UTC)[reply]

References

Etymology

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The source cited, "Advanced Therapy in Hypertension and Vascular Disease" by Mohler ER (2006), lacks relevance in the field of linguistics as it falls under the category of medical literature. In Greek, the term for lightning is actually written as ἀστραπή (astrapḗ). As per the LSJ Dictionary, the Greek term ἔκλαμψις (éklampsis), which corresponds to "eclampsia," encompasses two meanings: 1) shining forth or brightness and 2) metaphorically, sudden development. – Mariâ Magdalina (talk) 18:07, 4 September 2023 (UTC)[reply]

Wiki Education assignment: Exercise Physiology in Aging, ES4300-02

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This article is currently the subject of a Wiki Education Foundation-supported course assignment, between 12 August 2024 and 2 December 2024. Further details are available on the course page. Student editor(s): Wyatt.watkins1 (article contribs).

— Assignment last updated by B17rad (talk) 19:55, 14 November 2024 (UTC)[reply]